apurinic DNA

См. также в других словарях:

• DNA-(apurinic or apyrimidinic site) lyase — Identifiers EC number 4.2.99.18 CAS number 61811 29 8 …   Wikipedia

• DNA glycosylase — DNA glycosylases are a family of enzymes involved in base excision repair, classified under EC number EC 3.2.2. Base excision repair is the mechanism by which damaged bases in DNA are removed and replaced. DNA glycosylases catalyze the first step …   Wikipedia

• apurinic acid — DNA from which the purine bases have been removed by mild acid treatment …   Medical dictionary

• DNA polymerase beta — Polymerase (DNA directed), beta PDB rendering based on 1bno …   Wikipedia

• apurinic sites — Sites in DNA from which purines have been lost by cleavage of the deoxy ribose N glycosidic linkage …   Dictionary of molecular biology

• SOS system — The DNA repair system also known as error prone repair in which apurinic DNA molecules are repaired by incorporation of a base that may be the wrong base but that permits replication. RecA protein is required for this type of repair. SOS genes… …   Dictionary of molecular biology

• APEX1 — APEX nuclease (multifunctional DNA repair enzyme) 1, also known as APEX1, is a human gene. PBB Summary section title = summary text = Apurinic/apyrimidinic (AP) sites (also called abasic sites ) occur frequently in DNA molecules by spontaneous… …   Wikipedia

• AP endonuclease — An AP endonuclease is an enzyme that cuts a strand of DNA on the 5 side of an AP (apurinic/apyrimidinic) site, as the first step in DNA base excision repair (BER).AP endonucleases are divided into two families based on their homology to the… …   Wikipedia

• Mutagenesis — (pronounced /mjuːtəˈdʒɛnɪsɪs/) is a process by which the genetic information of an organism is changed in a stable manner, resulting in a mutation. It may occur spontaneously in nature, or as a result of exposure to mutagens. It can also be… …   Wikipedia

• Activation-Induced (Cytidine) Deaminase — (AID) is a 24 kDa enzyme that removes the amino group from the cytidine base in DNA.AID is currently thought to be the master regulator of secondary antibody diversification. It is involved in the initiation of three separate immunoglobulin (Ig)… …   Wikipedia

• Depurination — In molecular genetics, depurination is an alteration of DNA in which the purine base (adenine or guanine) is removed from the deoxyribose sugar by hydrolysis of the beta N glycosidic link between them. After depurination, an apurinic site is… …   Wikipedia